Efektifitas terapi refleksi dalam menurunkan fatigue pada pasien kanker: Systematic review
DOI: https://doi.org/10.56922/quilt.v5i2.963
Fatigue Kanker Kelelahan Terapi Komplementer Terapi Refleksi
Abstract
Background: Fatigue is one of the most common and disturbing symptoms experienced by cancer patients during and after treatment. Reflexology as a complementary intervention is increasingly being studied for its ability to improve the quality of life of patients, including reducing fatigue.
Purpose: To systematically review the effectiveness of reflexology therapy in reducing fatigue levels in cancer patients based on the latest scientific evidence.
Methods: A systematic literature search was conducted in PubMed, ScienceDirect, and Google Scholar databases using the keywords “reflexology”, “cancer”, and “fatigue”. Included articles were quantitative studies published in 2015–2024 using reflexology interventions in cancer patients, and measuring fatigue as one of the main variables. Article selection followed the PRISMA guidelines, and the final eight studies were analyzed qualitatively.
Results: Eight articles were analyzed, seven of which showed significant results that reflexology therapy can significantly reduce fatigue. The types of cancer studied varied, ranging from breast, lung, colorectal, to gynecological cancer. Reflexology therapy was carried out with a frequency of between two and five times per week for two to six weeks. Although there was one study that did not show significant results, overall reflexology therapy was considered effective and safe as a complementary approach.
Conclusion: Reflexology therapy has been shown to be generally effective in reducing fatigue in cancer patients. This intervention can be part of a holistic approach to cancer care.
Keywords: Cancer; Complementary Therapy; Fatigue; Reflection Therapy.
Pendahuluan: Fatigue merupakan salah satu gejala paling umum dan mengganggu yang dialami pasien kanker selama dan setelah menjalani pengobatan. Terapi refleksi sebagai intervensi komplementer semakin banyak diteliti karena kemampuannya dalam meningkatkan kualitas hidup pasien, termasuk dalam mengurangi kelelahan.
Tujuan: Untuk mengkaji secara sistematik efektivitas terapi refleksi dalam menurunkan tingkat fatigue pada pasien kanker berdasarkan bukti-bukti ilmiah terbaru.
Metode: Penelusuran literatur dilakukan secara sistematis pada database PubMed, ScienceDirect, dan Google Scholar menggunakan kata kunci “reflexology”, “cancer”, dan “fatigue”. Artikel yang dimasukkan adalah studi kuantitatif yang dipublikasikan tahun 2015–2024 dengan menggunakan intervensi refleksi pada pasien kanker, dan mengukur fatigue sebagai salah satu variabel utama. Seleksi artikel mengikuti pedoman PRISMA, dan delapan studi akhir dianalisis secara kualitatif.
Hasil: Delapan artikel yang dianalisis, tujuh di antaranya menunjukkan hasil signifikan bahwa terapi refleksi dapat menurunkan fatigue secara bermakna. Jenis kanker yang diteliti bervariasi, mulai dari kanker payudara, paru, kolorektal, hingga ginekologi. Terapi refleksi dilakukan dengan frekuensi antara dua hingga lima kali per minggu selama dua hingga enam minggu. Meskipun terdapat satu studi yang tidak menunjukkan hasil signifikan, secara keseluruhan terapi refleksi dinilai efektif dan aman sebagai pendekatan komplementer.
Simpulan: Terapi refleksi terbukti secara umum efektif dalam menurunkan kelelahan pada pasien kanker. Intervensi ini dapat menjadi bagian dari pendekatan holistik dalam perawatan kanker.
Kata Kunci: Fatigue; Kanker; Kelelahan; Terapi Komplementer; Terapi Refleksi.
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References
Abolwafa, N. F., Hasan, A. S. G., & Shehata, H. B. (2024). Effect of Foot Reflexology on Fatigue, Pain and Insomnia among Children undergoing Chemotherapy. Egyptian Journal of Health Care, 15(1), 169-179.
Alizadeh, J., Yeganeh, M. R., Pouralizadeh, M., Roushan, Z. A., Gharib, C., & Khoshamouz, S. (2021). The effect of massage therapy on fatigue after chemotherapy in gastrointestinal cancer patients. Supportive Care in Cancer, 29(12), 7307-7314.
Brown, J. S., Amend, S. R., Austin, R. H., Gatenby, R. A., Hammarlund, E. U., & Pienta, K. J. (2023). Updating the definition of cancer. Molecular Cancer Research, 21(11), 1142-1147.
Dikmen, H. A., & Terzioglu, F. (2019). Effects of reflexology and progressive muscle relaxation on pain, fatigue, and quality of life during chemotherapy in gynecologic cancer patients. Pain Management Nursing, 20(1), 47-53.
Eladham, M. A., Ismail, M. F., Eweda, S. M., Mohamed, M. A. F., & Elsayed, N. F. (2021). The Effect of Foot Reflexology on Chemotherapy Induced Nausea, Vomiting and Fatigue among Breast Cancer Patient. International Journal of Novel Research in Healthcare and Nursing, 8(1), 61–67.
Hassan, E. M., & DeRosa, M. C. (2020). Recent advances in cancer early detection and diagnosis: Role of nucleic acid based aptasensors. TrAC Trends in Analytical Chemistry, 124, 115806.
Hesami, M., Kalhor, M., Roshani, D., & Fathi, M. (2019). The Effect of Reflexology on Fatigue in Cancer Patients Receiving Chemotherapy: A Randomized Controlled Trial. Crescent Journal of Medical & Biological Sciences, 6(2).
Irmak, Z., Tanrıverdi, Ö., Ödemiş, H., & Uysal, D. D. (2019). Use of complementary and alternative medicine and quality of life of cancer patients who received chemotherapy in Turkey. Complementary therapies in medicine, 44, 143-150.
Klaus, M., Kutschan, S., Männle, H., Hübner, J., & Dörfler, J. (2024). Reflexology in oncological treatment–a systematic review. BMC complementary medicine and therapies, 24(1), 32.
Li, J., Fu, R., Guo, X., Pan, Z., & Xie, J. (2023). Acupuncture improves immunity and fatigue after chemotherapy in breast cancer patients by inhibiting the Leptin/AMPK signaling pathway. Supportive Care in Cancer, 31(9), 506.
Mazloum, S. R., Rajabzadeh, M., Mohajer, S., Bahrami-Taghanaki, H., & Namazinia, M. (2023). Comparing the effects of warm footbath and foot reflexology on the fatigue of patients undergoing radiotherapy: a randomized clinical trial. Integrative Cancer Therapies, 22, 15347354231172940.
Mohammed, A. A. E., Ayed, M. M. A, Hegazy, A. E. A., El-husseiny, H. S. A., & Amin, F. A. (2022). Effect of Foot Massage on Physiological Indicators, Fatigue, and Pain among Children undergoing Chemotherapy. Egyptian Journal of Health Care, 13(4), 26-39.
Murat-Ringot, A., Souquet, P. J., Subtil, F., Boutitie, F., Preau, M., & Piriou, V. (2021). The effect of foot reflexology on Chemotherapy-Induced nausea and vomiting in patients with digestive or lung cancer: Randomized controlled trial. JMIR cancer, 7(4), e25648.
Muthanna, F. M., Hassan, B. A. R., Karuppannan, M., Ibrahim, H. K., Mohammed, A. H., & Abdulrahman, E. (2023). Prevalence and impact of fatigue on quality of life (QOL) of cancer patients undergoing chemotherapy: a systematic review and meta-analysis. Asian Pacific journal of cancer prevention: APJCP, 24(3), 769.
Najafpour, Z., & Shayanfard, K. (2020). Effect of Reflexology in Treating Cancer Pain: A Meta-Analysis. International Journal of Cancer Management, 13(7).
Parizad, N., Hassanpour, A., Goli, R., Khalkhali, H., & Nozad, A. (2024). Comparing the impact of acupressure and reflexology on fatigue in chronic lymphocytic leukemia patients: a randomized controlled trial with three arms. European Journal of Oncology Nursing, 70, 102573.
Puspitaningtyas, H., Espressivo, A., Hutajulu, S. H., Fuad, A., & Allsop, M. J. (2021). Mapping and visualization of cancer research in Indonesia: a scientometric analysis. Cancer Control, 28, 10732748211053464.
Sari, N. P. W. P., & Mare, A. C. B. (2022). Predictors of Quality of Life of Family Caregiver in A Community Setting: Breast and Cervical Cancer Impacts. Indonesian Journal of Cancer, 16(4), 210-216.
Shan, S., Lin, L., Fang, Q., Tian, F., Guo, D., Zhou, Y., & Tian, L. (2023). Massage therapy significantly improves cancer-related fatigue in cancer patients: a meta-analysis of randomized controlled trials. Supportive Care in Cancer, 31(8), 464.
Shoghi, M., Asadian, A., & Kheradmand, M. (2024). The Effects of Foot Reflexology and Simple Foot Massage on Fatigue and Pain in Children With Leukemia: A Randomized Control Trial. Iranian Journal of Health Sciences, 12(1), 69-78.
Wanchai, A., & Armer, J. M. (2020). A systematic review association of reflexology in managing symptoms and side effects of breast cancer treatment. Complementary therapies in clinical practice, 38, 101074.
World Health Organization. (2021). Cancer in Indonesia. In International Agency for Reseach Cancer (Vol. 247, Issue 22, pp. 3087–3088). diakses dari: https://doi.org/10.1001/jama.247.22.3087
Wyatt, G., Lehto, R., Guha-Niyogi, P., Brewer, S., Victorson, D., Pace, T., Badger, T., & Sikorskii, A. (2021). Reflexology and meditative practices for symptom management among people with cancer: Results from a sequential multiple assignment randomized trial. Research in Nursing and Health, 44(5), 796–810.
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