Hubungan kadar SGOT dan SGPT pada petani tembakau
DOI: https://doi.org/10.56922/quilt.v6i6.2988
Liver SGOT SGPT Tobacco Farmers
Abstract
Background: Tobacco farmers are at high risk of exposure to toxic substances from tobacco, nicotine, and agricultural chemicals, which can affect liver function. Impaired liver function can be characterized by elevated levels of Serum Glutamic Oxaloacetic Transaminase (SGOT) and Serum Glutamic Pyruvic Transaminase (SGPT).
Purpose: To determine the relationship between SGOT and SGPT levels in tobacco farmers.
Method: This study used an observational analytical method with a cross-sectional design. A sample of 35 respondents was selected using a purposive sampling technique. Data were obtained through interviews and laboratory examination of SGOT and SGPT levels using the enzymatic kinetic method with a chemistry analyzer based on the IFCC (International Federation of Clinical Chemistry) method. Data were analyzed using the Shapiro-Wilk normality test followed by the Spearman correlation test.
Results: 26 respondents (74.3%) had normal SGOT levels (<50 U/L), and 24 respondents (68.8%) had normal SGPT levels (<50 U/L). Spearman's test results showed a significant positive relationship between SGOT and SGPT levels, with a correlation coefficient of r = 0.833 and a significance value of p = 0.000 (p < 0.05).
Conclusion: There is a significant relationship between SGOT and SGPT levels in tobacco farmers.
Keywords: Liver; SGOT; SGPT; Tobacco Farmers.
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