Risk factor analysis of type 2 diabetes mellitus in rural areas: A systematic review
DOI: https://doi.org/10.33024/minh.v8i5.974
Diabetes Risk Factors Rural Area
Abstract
Background: Type 2 diabetes mellitus (DM) prevalence continues to increase in rural areas, which is of particular concern due to limited access to health services in these areas.
Purpose: To identify various risk factors for the incidence of type 2 DM in rural areas for the development of effective prevention programs.
Method: Systematic review is based on PRISMA guidelines. Searches were conducted in Scopus, Science Direct, and SINTA for 2020-2025 articles. Data were extracted and analyzed narratively based on the type of risk factors that were found.
Results: Out of 856 articles, 20 studies met the inclusion criteria. Dominant risk factors identified included obesity (OR range 2.15-3.05), family history of DM (OR range 2.13-4.46), and low physical activity (OR range 2.94-7.43). Additional risk factors include hypertension, unhealthy food environment, and unhealthy diet. Several studies reported an increased incidence of type 2 DM in younger populations in rural areas.
Conclusion: Obesity, family history of DM, and low physical activity are the dominant risk factors for type 2 DM in rural areas. These factors are important targets for health policy interventions, especially given the increasing incidence in younger populations in rural areas.
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Al-Mohaithef, M., Abdelmohsen, S. A., Algameel, M., & Abdelwahed, A. Y. (2022). Screening for identification of patients at high risk for diabetes-related foot ulcers: a cross-sectional study. Journal of International Medical Research, 50(3), 03000605221087815.
Feyissa, T. R., Wood, S. M., Vakil, K., Namara, K. M., Coffee, N. T., Alsharrah, S., & Versace, V. L. (2024). The built environment and its association with type 2 diabetes mellitus incidence: A systematic review and meta-analysis of longitudinal studies. Social Science & Medicine, 361, 117372.
Gebang, A. A. (2021). Hubungan faktor aktivitas fisik dengan kejadian penyakit diabetes melitus tipe 2 di Kabupaten Sikka Provinsi Nusa Tenggara Timur Tahun 2021.
Gherbon, A., Frandes, M., Nicula-Neagu, M., Timar, R., & Timar, B. (2023). The implications of the pandemic with Covid-19 in the glycemic control of people with type 2 diabetes. Diabetes, Metabolic Syndrome and Obesity, 4109-4118.
Homsana, A., Southisavath, P., Kling, K., Hattendorf, J., Vorasane, S., Paris, D. H., & Probst-Hensch, N. (2024). Steatotic liver disease among lean and non-lean individuals in Southern Lao PDR: a cross-sectional study of risk factors. Annals of Medicine, 56(1), 2329133.
Issaka, A., Paradies, Y., Cameron, A. J., & Stevenson, C. (2024). The association between body weight indices, behavioral factors, and type 2 diabetes mellitus in Africa: a systematic review and meta-analysis of population-based epidemiological studies. Nutrition, Metabolism and Cardiovascular Diseases, 34(1), 1-18.
Jabbar, P. K., Nair, A., Chellamma, J., Jayakumar, R. V., Ramesh, J., Gomez, R., & Vijayakumar, K. (2023). Type 2 diabetes and precursors in community dwelling Asian Indian adult youth. Indian Journal of Endocrinology and Metabolism, 27(4), 307-314.
Jati, R. A., Muchtar, F., & Salsabila, S. (2023). Faktor Risiko Aktivitas Fisik Pada Kejadian Diabetes Melitus Tipe 2 di Wilayah Kerja Puskesmas Kemaraya Kota Kendari Tahun 2023. KOLONI, 2(2), 328-334.
Jeffries-Stokes, C. A., Stokes, A. M., McDonald, L., Evans, S., Anderson, L., & Robinson, P. M. (2020). Risk factors for renal disease and diabetes in remote Australia–findings from The Western Desert Kidney Health Project. Rural and Remote Health, 20(2), 27-38.
Lintang S, A. A., Mutiara, H., & Falamy, R. (2019). Hubungan Antara Lama Menderita Diabetes Melitus Tipe 2 Dengan Kejadian Peripheral Arterial Disease Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Kedaton Kota Bandar Lampung. MEDULA, medicalprofession journal of lampung university, 9(2), 379-384.
Maimaitituerxun, R., Chen, W., Xiang, J., Xie, Y., Kaminga, A. C., Wu, X. Y., & Dai, W. (2023). 使用列线图筛查 2 型糖尿病轻度认知障碍. Journal of Diabetes, 15(5), 448-458.
Motala, A. A., Mbanya, J. C., Ramaiya, K., Pirie, F. J., & Ekoru, K. (2022). Type 2 diabetes mellitus in sub-Saharan Africa: challenges and opportunities. Nature Reviews Endocrinology, 18(4), 219-229.
Muhammad Junaid, M. J., Fawad Ahmed, F. A., Ziaur Rehman, Z. R., Irfan Ali, I. A., & Tayyaba Arshad, T. A. (2024, November). The Impact of Type 2 Diabetes Mellitus Duration on Diminishing Visual Acuity in Pakistan. In Medical Forum Monthly (Vol. 35, No. 11).
Nanditha, A., Susairaj, P., Satheesh, K., Raghavan, A., Snehalatha, C., & Ramachandran, A. (2024). The rising prevalence of type 2 diabetes among the youth in southern India—An ancillary analysis of the Secular TRends in DiabEtes in India (STRiDE‐I) study. Journal of Diabetes, 16(7), e13576.
Parera, Y. F., Hinga, I. A. T., & Riwu, Y. R. (2023). Analisis Faktor Risiko Yang Berhubungan dengan Kejadian Diabetes Melitus Tipe 2 di Wilayah Kerja Puskesmas Oesapa Kota Kupang Tahun 2023. Sehatmas: Jurnal Ilmiah Kesehatan Masyarakat, 2(4), 991-1000.
Ruiz-Alejos, A., Carrillo-Larco, R. M., Miranda, J. J., Gilman, R. H., Smeeth, L., & Bernabé-Ortiz, A. (2020). Skinfold thickness and the incidence of type 2 diabetes mellitus and hypertension: an analysis of the PERU MIGRANT study. Public health nutrition, 23(1), 63-71.
Taja, L. E. C., Ndoen, H. I., & Ndun, H. J. (2024). Hubungan Genetik, Kebiasaan Merokok, dan Aktivitas Fisik dengan Kejadian Diabetes Melitus Tipe 2 pada Lansia di Wilayah Kerja Puskesmas Sikumana Tahun 2021. SEHATMAS: Jurnal Ilmiah Kesehatan Masyarakat, 3(3), 515-521.
Wang, B., Liu, L., Qiao, D., Xue, Y., Liu, X., Zhang, D., & Li, X. (2020). The association between frequency of away-from home meals and type 2 diabetes mellitus in rural Chinese adults: the Henan Rural Cohort Study. European Journal of Nutrition, 59(8), 3815-3825.
Xue, Y., Liu, C., Wang, B., Mao, Z., Yu, S., Wang, Y., & Li, X. (2021). The association between dietary patterns with type 2 diabetes mellitus and pre-diabetes in the Henan rural cohort study. Public Health Nutrition, 24(16), 5443-5452.
Yu, J., Yi, Q., Chen, G., Hou, L., Liu, Q., Xu, Y., & Song, P. (2022). The visceral adiposity index and risk of type 2 diabetes mellitus in China: a national cohort analysis. Diabetes/metabolism research and reviews, 38(3), e3507.
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