A comparative study of processed Moringa leaves and Fe tablet supplementation on hemoglobin levels among mildly anemic pregnant women
DOI: https://doi.org/10.33024/minh.v8i9.1212
Experiment FE Tablets Hemoglobin Moringa Leaves
Abstract
Background: Anemia is a condition characterized by hemoglobin (Hb) levels below normal physiological values based on age and sex. Among pregnant women, anemia poses serious health risks to both the mother and the fetus, including miscarriage, preterm birth, infection, hemorrhage, intrauterine fetal death, low birth weight, congenital anomalies, perinatal mortality, and reduced infant intelligence. In Bekasi City, the prevalence of anemia among pregnant women increased from 14.3% in 2021 to 20% in 2022, largely due to poor adherence to iron (Fe) tablet supplementation, often caused by side effects such as nausea and unpleasant taste.
Purpose: To compare the effectiveness of processed Moringa leaves (Moringa oleifera) and Fe tablets in improving hemoglobin levels among pregnant women with mild anemia.
Method: A quantitative experimental design with a two-group pretest–posttest approach was used. The study was conducted at Mrs. Ida Roningsih’s Independent Midwife Practice from August 1 to September 31, 2024, involving all pregnant women in the working area, totaling 44 participants. Data were collected through hemoglobin measurements before and after intervention and questionnaire responses. Statistical analyses included univariate and bivariate analysis, the Shapiro–Wilk normality test, and T-test or Wilcoxon test as appropriate.
Results: The mean increase in hemoglobin levels among pregnant women in the Moringa leaf group was 1.35 g/dL (6.15%), compared to only 0.09 g/dL (0.4%) in the Fe tablet group. A significant difference was observed between the intervention and control groups (p = 0.000). The relative risk (RR) of 2.375 indicates that pregnant women receiving Moringa leaf capsules were 2.375 times more likely to experience an increase in Hb levels compared to those taking Fe tablets.
Conclusion: Processed Moringa leaves (Moringa oleifera) were proven to be more effective than Fe tablets in increasing hemoglobin levels among pregnant women with mild anemia, showing a more than twofold greater improvement in Hb levels.
Downloads
References
Agustini, N. K. F., Sunarsih, S., Rachmawati, F., & Astriana, A. (2024). Comparison of The Effectiveness of Moringa and Spinach Leaf Capsules in Increasing Hemoglobin Levels among Anemic Pregnant Women in The Third. JKM (Jurnal Kebidanan Malahayati), 10(4), 315-323.
Badri, B. F., Indarto, D., Ardyanto, T. D., & Avelia, A. (2024). The Beneficial Effect of Moringa Oleifera Leaves on Hemoglobin Levels in Pregnant Women with Anemia: A Systematic Review. Jurnal Aisyah: Jurnal Ilmu Kesehatan, 9(1). Retrieved from: https://aisyah.journalpress.id/index.php/jika/article/view/2650
Bloor, S. R., Schutte, R., & Hobson, A. R. (2021). Oral iron supplementation—gastrointestinal side effects and the impact on the gut microbiota. Microbiology Research, 12(2), 491-502.
Djaba, E. S. S., & Marfu’ah, S. (2023). Pengaruh Pemberian Sayur Daun Kelor Terhadap Peningkatan Kadar Hemoglobin Pada Ibu Hamil. Cendekia Medika: Jurnal Stikes Al-Maarif Baturaja, 8(1), 73-87.
Kahirah, R., Nashrillah, M. P., Royani, I., Susanti, R., Riance, W., & Lasmita, W. (2024). Effectiveness of Consumption of Moringa Leaves, Fe Tablets with Dates and Fe Tablets Against Increasing Hemoglobin in Pregnant Women with Anemia. Jurnal Penelitian Pendidikan IPA, 10(10), 7267-7275.
Kalam, E. M., Noor, N. M., Ishak, A., & Yusoff, S. S. M. (2024). Moringa oleifera supplementation for anemic pregnant women: A Systematic Review and Meta-analysis. Bangladesh Journal of Medical Science, 23(3), 597-609.
Ministry of Health of the Republic of Indonesia. (2013). Laporan Riset Kesehatan Dasar (RISKESDAS) tahun 2013 dalam bentuk angka. Badan Penelitian dan Pengembangan Kesehatan, Jakarta. Retrieved from: https://repository.badankebijakan.kemkes.go.id/id/eprint/4428/
Ministry of Health of the Republic of Indonesia. (2019). Profil Kesehatan Indonesia 2018. Retrieved from: https://www.kemkes.go.id/downloads/resources/download/pusdatin/profil-kesehatan-indonesia/profil-kesehatan-indonesia-2018.pdf
Ministry of Health of the Republic of Indonesia. (2020). Pedoman pelayanan antenatal terpadu. Jakarta. Kementerian Kesehatan RI. Retrieved from: https://repository.kemkes.go.id/book/147
Lenau, M., Hardiningsih, E. F., Hartati, D., & Sulistyorini, C. (2023). Hubungan Anemia Pada Kehamilan Dengan Kejadian Perdarahan Pasca Bersalin dan BBLR di RSUD dr. Abdul Rivai. Humantech: Jurnal Ilmiah Multidisiplin Indonesia, 2(5), 861-878.
Manggul, M. S., Hidayanty, H., Arifuddin, S., Ahmad, M., Hadju, V., & Usman, A. N. (2021). Biscuits containing Moringa oleifera leaves flour improve conditions of anemia in pregnant women. Gaceta Sanitaria, 35, S191-S195.
Muhayati, A., & Ratnawati, D. (2019). Hubungan antara status gizi dan pola makan dengan kejadian anemia pada remaja putri. Jurnal Ilmiah Ilmu Keperawatan Indonesia, 9(01), 563-570.
Retnorini, D. L., Widatiningsih, S., & Masini, M. (2017). Pengaruh pemberian tablet fe dan sari kacang hijau terhadap kadar hemoglobin pada ibu hamil. Jurnal kebidanan, 6(12), 8-16.
Rishel, R. A. (2023). Pengaruh Pemberian Kapsul Daun Kelor (Moringa Oleifera) Terhadap Kadar Hemoglobin Ibu Hamil Dengan Anemia. Jurnal Ilmu Keperawatan dan Kebidanan, 14(1), 187-192.
Sari, N., Sulastri, D., & Endrinaldi, E. (2023). Differences in the Effect of Giving Fe Tablets and Capsules Moringa Leaves on Hepcidin and Ferritin Levels in Anemic Pregnancy Rats. Contagion: Scientific Periodical Journal of Public Health and Coastal Health, 5(3), 924-937.
Siagian, C. M., Djogo, M. F., Nahak, M. M., Tedjasulaksana, R., Manek, A. E., Sormin, E., & Pieter, L. A. G. (2023). Supplementation of Moringa (Moringa oleifera) leaf capsules on hemoglobin levels in women of reproductive age with iron deficiency anemia in Malaka regency, Nusa Tenggara Timur, Indonesia. Bali Medical Journal, 12(3), 2383-2385.
Sitepu, T. J., Pangestu, G. K., & Febriyani, P. A. (2024). Efektivitas Pemberian Ekstrak Daun Kelor Kombinasi Fe dan Fe terhadap Peningkatan Hb Remaja Putri di Poltekes TNI AU Ciumbuleuit Bandung 2024. Jurnal Penelitian Inovatif, 4(3), 1195-1202.
Suheti, E., Indrayani, T., & Carolin, B. T. (2020). Perbedaan pemberian jus daun kelor (Moringa oleifera) dan kacang hijau (vigna radiata) terhadap ibu hamil anemia. Jurnal akademi keperawatan husada karya jaya, 6(2), 1-10. Retrieved from: https://ejurnal.husadakaryajaya.ac.id/index.php/JAKHKJ/article/view/145
Usman, U., & Umar, F. (2022). The Effectiveness of Giving Moringa Oleifera Formulation to Increase Hemoglobin Levels in Pregnant Women. Jurnal Ilmiah Kesehatan (Jika), 4(2), 232-238.
World Health Organization. (2024a). Maternal Mortality. Retrieved from: https://www.who.int/news-room/fact-sheets/detail/maternal-mortality.
World Health Organization. (2024b). WHO Global Anaemia estimates, 2024 Edition. Retrieved from: https://www.who.int/data/gho/data/themes/topics/anaemia_in_women_and_children
Zubaydah, W. O. S., Fia, W., Adawia, S., Novitasari, N., Rahmasari, R., & Hasanuddin, D. D. (2019). Formulasi Minuman Effervescent Mix Serbuk Daun Kelor (Moringa oleifera). Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan, 4(2), 2-4. Retrieved from: https://ojs.uho.ac.id/index.php/pharmauho/article/view/6281
Downloads
Published
Issue
Section
License
Copyright (c) 2025 Sari Narulita, Royani Chairiyah

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.