Usia dan riwayat reproduksi sebagai prediktor kejadian kanker serviks

DOI: https://doi.org/10.33024/hjk.v20i6.4193

Authors

  • Rina Sulisthia Arbie Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Yollanda Dwi Santi Violentina Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Selvi Mohamad Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Veny Delvia Pombaile Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Ni Made Dewi Anggraeni Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Desak Made Yulianti Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo
  • Ika Suherlin Jurusan Kebidanan, Poltekkes Kemenkes Gorontalo

Age Age at First Childbirth Age at Menarche Cervical Cancer

Abstract

Background: Cervical cancer remains a leading cause of cancer-related death among women worldwide. Reproductive risk factors such as age, age at menarche, and age at first childbirth are considered important determinants of its incidence, particularly in developing countries with limited screening coverage.

Purpose: To analyze age and reproductive history (age at menarche and age at first childbirth) as predictors of cervical cancer incidence.

Method: This study employed an observational analytic design with a case-control approach. It was conducted at Aloe Saboe Hospital between August and December 2025. The sample consisted of 18 women with cervical cancer (case group) and 18 women without cervical cancer (control group), selected through a review of medical records. Data were analyzed using the Chi-Square test, calculating the odds ratio (OR) and 95% confidence interval (CI) at a significance level of p < 0.05.

Results: Age at menarche was significantly associated with the incidence of cervical cancer (p = 0.001; OR = 2.543; 95% CI: 1.621–3.991). Age (p = 0.396; OR = 1.225; 95% CI: 0.808–1.859) and age at first childbirth (p = 0.760; OR = 0.428; 95% CI: 0.224–0.817) did not show a statistically significant association.

Conclusion: Early age at menarche is a significant predictor of cervical cancer incidence, whereas age and age at first childbirth did not show a significant association in this sample. Early detection efforts should be prioritized for women with a history of early menarche.

Suggestion: Future research should be conducted with a larger sample size and multivariate analysis to control for confounding variables particularly the age at first childbirth, which involved small subgroups in this study in order to obtain more accurate and generalizable risk estimates.

 

Keywords: Age; Age at First Childbirth; Age at Menarche; Cervical Cancer.

 

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Published

2026-08-31

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Vol. 20 No. 6 (2026): Volume 20 Nomor 6

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